Publisher Arc System Works and developer Wayforward announced River City Girls Zero, known as Shin Nekkeketsu Koha: Kunio-tachi no Baka in Japan. This localized version will launch on the Nintendo Switch in late 2021, with other platforms to follow shortly. In addition, Limited Run Games announced they would produce a physical version.

Here is an overview of the game from WayForward:

River City Girls Zero, meanwhile, lets players experience the first time that Misako and Kyoko teamed up with Kunio and Riki to take to the streets in hard-hitting, curb-stomping action. While the graphics, music, and gameplay all remain faithful to the classic 16-bit Super Famicom release, this version marks the first time the 1994 game will be localized for the West. A new opening cinematic, new manga cutscenes, and a new theme song by River City Girls composer Megan McDuffee have been added as well. Set out solo or team up with a friend in local co-op and discover how the River City Girls story began!