Probably the most badass otaku hero to grace gaming console, Travis Touchdown, will be returning in No More Heroes Deperate Struggle. Announced earlier today at the Tokyo Game Show 2008, little else is known about the title, with no release date or console information though probably on the Wii.
Some speculate that it may be a DS spinoff due to the title "Desperate Stuggle"; however, the trailer specifically labels the game as "NMH2" for No More Heroes 2.
Update: Confirmed that this game will be for the Wii and two versions of the game will be released, one with heavy blood while the other will be censored.
Trailer included inside.